The CNRS is hosting 6 ERC 'Proof of Concept' 2025 grantees
Half of the 12 French grant-winners in the European Research Council's (ERC) 'Proof of Concept' first call for 2025 come from the CNRS.
ERC Proof of Concept 2025 : 2 recipients at CNRS Physique
Europe and International
Distinction
Leïla Perié, CNRS senior researcher at the Physique des cellules et cancer (PCC) laboratory, and Valentina Emiliani, CNRS senior researcher and physicist at the Vision Institute, are winners of the ERC Proof of Concept 2025 grant, which rewards established and recognised researchers in their field.
VisioWell - Un dispositif d’imagerie à haut débit pour les cellules non adhérentes
VisioWell aims to overcome a major technological obstacle: enabling real-time, large-scale observation of the behaviour of cells that move freely in a liquid, such as blood cells, immune cells, and certain cancer cells. Unlike tissue cells, these cells do not attach to each other or to a substrate: they are referred to as non-adherent cells.
The VisioWell project is led by Leïla Perié
Leïla Perié is CNRS senior researcher at the Physique des cellules et cancer (PCC, CNRS / Institut Curie / Sorbonne Université) laboratory.
2P-MINOPS - Two-photon miniaturized integrated neuro-optical photon system for neuronal circuits investigaiton in freely moving primates
The optogenetics revolution began with the discovery of light-sensitive proteins (opsins) that can be activated by light. Their use makes it possible to control the activity of specific neuronal populations, enabling functional mapping of the brain for the first time. However, the field illumination traditionally used in optogenetics activates large populations of neurons synchronously and does not achieve the precision needed to reproduce the complex, natural firing patterns of neural circuits. To overcome this limitation, Emiliani's laboratory has developed ‘circuit optogenetics,’ combining computer-generated holography, temporal focusing, and two-photon excitation. This technique enables optogenetic control of neural circuits with millisecond temporal precision and spatial precision that allows single cells deep within brain tissue to be targeted. These methods have enabled the mapping and manipulation of neural circuits in mice with unprecedented precision.
Le projet 2P-MINOPS est porté par Valentina Emiliani
Valentina Emiliani is CNRS senior researcher at the Institut de la Vision (IdV, CNRS / INSERM / Sorbonne Université).
All CNRS Physics PoC ERCs
Discover all the ERC Proof of Concept recipients at CNRS Physics.
Contact
Valentina Emiliani
Directrice de recherche CNRS à l'Institut de la Vision
Leïla Perié
Directrice de recherche CNRS au laboratoire Physique des Cellules et Cancer (PCC)